This lecture on hepatoportal interpretation begins with a review of anatomy and physiology of the hepatoportal vessels. Disease states discussed include portal hypertension, coronary vein and esophageal varices, paraumbilical vein, collateral flow, intrahepatic and extrahepatic flow, and hepatofugal flow of the hepatic and splenic veins. Other topics include Budd-Chiari Syndrome, cavernous transformation of the portal vein, malignant portal vein thrombosis and normal and abnormal findings with TIPS.